*Edited* cause realised your post was about hyperspin , I haven't tried but if it uses the RocketLauncher UI , load up that and you can configure an exit emulator button combination in there under settings > main settings, hope this is of help and anyone please correct me if i'm wrong.

I Use CoinOps where you Press both Select & Start together for most emulators/games,  a few require large middle button & Start instead, this applies to Xbox Controllers and the EasySMX wireless controller which is a great alternative to an xbox xontroller, decent weight, rumble and response and a lot cheaper starting at £16.99 fully compatible psc=1">psc=1